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Tag: Adrenal Fatigue Treatment


Stress Induced Inflammation and the NEM Stress Response

What is Inflammation?

stress induced inflammation and its symptoms

Stress-induced inflammation is the result of the immune system’s cells and their byproducts attacking pathogens or damaged cells. This process increases blood flow to the affected area, creating redness and warmth. The substances the immune system’s cells release can cause a leakage of fluid into the tissues and produce swelling.

Pain and irritation may arise from this process. Other symptoms include fever, stiffness, tiredness, headaches, chills, sweating, dizziness, low appetite, and aches and pains in different areas, like joints.

Immune cells are found all over the body. Leukocytes (a type of white blood cell) are produced in the bone marrow and lymphocytes (also a type of white blood cell) are found in the lymphatic system.

However, most of the body’s immunity actually begins in the gut. The gut contains two-thirds of immune tissue in what is called the GI tract’s immune system – the gut-associated lymphoid tissue (GALT). The GALT is mainly located in the small intestine and is composed of different kinds of immune cells.

The immune system’s response can be divided into these main fields of operation: natural and specific immunity or cellular and humoral immunity.

Natural immunity is the general defense system against pathogens. It works by producing phagocytic cells, cytokines, and killer cells. Phagocytic cells, like neutrophils and macrophages, destroy infectious pathogens. Cytokines stimulate the cells needed in the immune response to move to the affected areas (sites of infections or injuries) and help these cells communicate. Natural killer cells (a subset of white blood cells also called NK) kill infected or cancerous cells important source.

Specific immunity targets specific “jobs” or threats. It includes NKs, B cells that create antibodies to support humoral immunity, and T helper cells that create cytokines to support cellular immunity.

With regard to cellular and humoral immunity, the difference is that cellular (also called cell-mediated immunity) tags and destroys intracellular pathogens, like viruses. It doesn’t involve antibodies, but antigen-specific Th1 lymphocytes, T cytotoxic cells, and NKs.

Humoral immunity on the other hand, which is immunity that involves substances found in extracellular fluids, deals with extracellular pathogens like bacteria or parasites. It does this through Th2 cytokines that stimulate B cells into producing antibodies and antimicrobial peptides that mark extracellular pathogens for disposal.

Stress and high cortisol levels affect the immune system. They promote proinflammatory pathways, especially the activity of Th2 cytokines, creating a Th1 to Th2 shift. This shift suppresses cellular immunity in favor of humoral immunity.

With chronic stress, both Th1 and Th2 classes of cytokines can dysregulate, causing the suppression of both types of immunity and be slowing down the healing of wounds, producing less effective defenses against viral and bacterial infections, longer recovery from surgery, and a decrease in the ability to kill cancer cells.

Without an optimally functioning immune response, the risk of low-grade and persistent inflammation is increased, even though the inflammation itself is no longer able to contain infections or help injury recovery as well as it should.

The rise in proinflammatory cytokines involved in stress-induced inflammation can also trigger the development of autoimmunity. These cytokines can stimulate the immune system to attack the body’s healthy cells, mistaking them for unhealthy cells or harmful intruders. Depending on which organ or system has been damaged by the immune response, you get a specific disease picture with its own set of symptoms.

For example, if the cytokines stimulate the immune system into attacking the respiratory airways, you can develop asthma. If the immune system attacks the pancreatic cells that produce insulin, you can develop type 1 diabetes.

Stress, when chronic in nature or when it comes at a time when an individual is in a fragile state (such as during certain hormonal changes for women like pregnancy or menopause, or when there is an illness present), can also trigger the development of autoimmunity and chronic disease.

The underlying connection is, as mentioned earlier, that chronic stress induces inflammation, and inflammation is at the root of these problems.

Stress, Inflammation, and Aging

Adrenal Fatigue Treatment

Adrenal Fatigue Treatment

Stress also has an effect on the aging process because inflammation has an effect on aging. Aging is caused by cellular senescence, which is the irreversible cell cycle arrest that comes from changes in the length and structures of telomeres.

Telomeres are the “caps” at the end of DNA strands; they are there to protect chromosomes. When these telomeres are shortened or changed, they cannot do their jobs as well and the DNA strands are exposed to damage.

Stress-induced inflammation can accelerate cellular senescence through progressive telomeric shortening as well as oxidative stress and oncogene activation. Oncogenes are genes that, when activated, have the capacity to cause cancer.

Aging has also been linked to an increase in free radicals, hormonal decline and the decline in mitochondrial adenosine triphosphate (ATP). ATP is thought of as the energy currency of life; it is the molecule that stores the energy needed for all biological processes. Mitochondria, the organelles found in cells, synthesize this life energy by breaking down carbohydrates and fatty acids.

With free radicals, you require antioxidants to neutralize them. If your system is overloaded with free radicals, antioxidants are no longer sufficient. As the cells are exhausted and not producing enough ATP, antioxidants cannot help much. Oxidative medicine may be the better alternative as it puts energy directly into the body again. The use of natural compounds that have metabolic cardiological properties such as ribose, magnesium, CoQ10, and carnitine may be helpful to the mitochondria in optimizing ATP function.

Adrenal Fatigue and Inflammation

As you can see, the interplay between stress, inflammation, and adrenal gland function are closely tied together.

Stress-induced inflammation is a huge stressor on the body – strong enough to trigger adrenal fatigue treatment or add to its many problematic symptoms like tiredness, depression, brain fog, food sensitivities and general weakness. All systems of the body are affected.

Because the NEM’s inflammation response includes the immune system, brain, and gut, its dysregulation from chronic stress will affect all of these components as well.

When these organs and systems are overworked, you not only get problems with them directly, but the adrenal glands will become overworked as well. When the adrenal glands cannot suppress this stress-induced inflammation, the cycle continues.

Throughout the article, we have mentioned a few tests and markers for stress, which can also help you determine whether you could develop stress-induced inflammation over time. There are also some specific ways to test for inflammation directly, using symptoms as well as markers.


Essential Strategies for Adrenal Fatigue Treatment

Modern life can be full of ongoing stressors from financial worries to relationship problems to work issues. In fact, stress has become one of the biggest complaints of the modern age. This is unfortunate because stress can have devastating effects on your mental, emotional and physical health. It can lead to a whole range of disorders such as cancer, heart attack, and inflammation. It can also cause long-term disorders such as Adrenal Fatigue Syndrome (AFS). This troubling and frustrating disorder can cause long-term health problems and ongoing damage to your quality of life. So if you think you have this disorder, you need to look at some of the options for Adrenal Fatigue treatment.

Adrenal Fatigue Treatment

Adrenal Fatigue Treatment

What is AFS?

AFS is a debilitating and ongoing disorder that can occur as a result of prolonged periods of stress. It causes a variety of troubling symptoms such as brain fog, fatigue that isn’t alleviated by rest periods, digestive problems, anxiety, and palpitations. These problems occur when your adrenal glands become fatigued because of overuse. Your adrenal glands are an important part of your neuroendometabolic (NEM) stress response. This is a system in your body that activates when you’re under stress. It makes changes that help protect your body from stress and prepares you to react to the threats that are causing the stress. But today’s threats aren’t predators that want to devour you. Instead, stress today is usually caused by a combination of lifestyle choices and factors, which makes it ongoing, and far more destructive.

When you’re under stress for a long time, it means that your neuroendometabolic (NEM) stress response is almost constantly active. Your adrenal glands are a vital part of this system, as they secrete a number of hormones that are essential for good functioning. But when the demand for these hormones is at a higher than normal level over a long period of time, the adrenal glands can become fatigued and struggle to keep up with the demand. The result is imbalances in the system that can cause a problem with every organ in and function of the body.

AFS isn’t commonly accepted by many medical professionals and this can create a problem when it comes to medical treatment for adrenal fatigue. Because of this, you may find it difficult to find a doctor who can accurately identify your disorder and offer options for adrenal fatigue treatment. Unfortunately, this may result in a long period of ill health and confusion as you struggle to understand what’s happening to you and how to start down the path of AFS recovery.

The Basics of Adrenal Fatigue Treatment

AFS usually takes a long time to develop, which means that the treatment for adrenal fatigue can take a long time as well. It also depends on your own physical condition and which stage of the illness you’re in. AFS has four distinct stages, ranging from the fairly mild stage one to stage five, which can be life-threatening. Giving yourself time and space to heal is key. There’s no point in pushing or trying to rush the process, as it will only cause more stress and more damage. During this time, it’s important that you look at your health and wellness in a holistic way, examining and making changes that will support your health and healing in every aspect of your life.

The best way to start your adrenal fatigue treatment is to take a multi-pronged approach. You need to both remove stressors from your life, avoid practices that can worsen your condition, and adjust other practices so they support rather than harm your healing. This means getting more sleep, changing your diet, and working on your mindset and mental practices to alleviate stress and pressure.

Dietary Changes for Adrenal Fatigue Treatment

There are a number of changes you need to make to your diet that will help with treatment for adrenal fatigue. These changes will assist with adrenal fatigue symptoms and treatment. A poor diet can increase the amount of stress your body experiences and deprive it of the nutrients and vitamins it needs to function properly and to heal. That’s why a big part of your recovery is this element of your adrenal fatigue treatment plan. Some general tips for the dietary changes you need to make are as follows:

· Make sure that you eat regularly and give your body the sugar it needs to function properly.

· 30-40 percent of your diet should consist of fresh vegetables.

· 20-30 percent of your diet should come from lean proteins. Just make sure these proteins are ethically sourced and hormone free.

· Another 20-30 percent of your diet should come from healthy fats such as nuts and seeds.

· The rest of your diet should consist of whole grains, fruits, beans, and legumes.

· Avoid caffeine and products that contain caffeine.

Medical Treatment for Adrenal Fatigue

You need to be careful when it comes to looking for medical treatment for adrenal fatigue. Any measures that you take to mask the symptoms, such as painkillers or the like, will only obscure what’s really going on with your body and make it more difficult for you to understand your condition. This approach can make your life better in the short term, but it also makes adrenal fatigue treatment more difficult over the long term. This doesn’t mean that you should completely dismiss your doctor and any recommendations they make as this could be very dangerous. Instead, you need to take control of your condition and do some research if you struggle to find an effective medical treatment for adrenal fatigue.

Final Thoughts

AFS can be a troubling and frustrating disorder. People who suffer from it often struggle to understand their condition and to find the adrenal fatigue treatment options they need. Treatment for adrenal fatigue isn’t easy, it requires a holistic view that takes into account every aspect of your life and practices. This means overhauling the way you eat, examining your mindset and practices, and sometimes even rethinking some of your lifestyle choices. Though this may sound radical, it’s also essential if you have AFS and want to get back your health and your quality of life.


Adrenal Fatigue Treatment Diet

The overall goal of adrenal fatigue treatment includes preventing further progression, resolving the unpleasant reactions, as well as, recovery programs.

Proper adrenal fatigue treatment is customized based on individual needs of each person and so, there are no standardized recovery protocols. The condition manifests with varying symptoms on each person, and also, body requirements differ from one person to another depending on body constitutions.

In addition, proper adrenal fatigue treatment guarantees full recovery and the person resumes normal productive life. In fact, almost all sufferers recover within a period of six months and two years depending on severity.

An ideal AF treatment protocol consists, but not limited to, diet, nutrition, exercise, and electrolyte adjustments.


1) Diet.

A person experiencing adrenal crash has imbalanced metabolism, hypoglycemia, and also compromised gastric assimilation. So, a dietary adjustment should major on how to stabilize blood sugar by balancing carbohydrate, protein, and fat in the diet. A proper delivery system of macro-nutritional form enhances both absorption and delivery of nutrients to the cells.

2) Nutrition.

When a person experiences a crash, the amount of nutrient to be recommended is based on clearance state, autonomic system sensitivity, history of paradoxical reaction, as well as, biological constitution. For example, a person with poor clearance levels will have reduced nutrients during the crash while those with normal clearance there nutrients levels will be increased during or immediately after a crash.

3) Exercise.

Unnecessary physical activity should be avoided and instead increase rest. Exercise is adjusted to match the energy state of the body. In early Adrenal Fatigue, Exercise enhances release of adrenaline as well as blood circulation which results in short-term energy boost and this always should be followed by sufficient rest. Over-exercise drains the body that trigger follow up crashes. In advanced AF, exercise is minimal and increases depending on how recovery is taking place. So, depending on the severity of the condition, each individual has customized exercise program.

4) Electrolyte Adjustments.

Salt craving is a common symptom in AF due to sodium imbalance caused by hormonal dysfunction. The imbalance worsens during a crash. According to adrenal fatigue treatment policy, the rebalance process should be carefully titrated and controlled to avoid worsening the situation.

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